Praziquantel (Drontal Plus)

Praziquantel

Antiparasitic
(Droncit, Drontal Plus, Sentinel Spectrum)
By Dr. Karen Burgess

• Praziquantel (generic formula)
• Droncit, Drontal Plus, Sentinel Spectrum (brand name animal formula)
• Tablet, Flavor Tablet, Injectable

What is praziquantel?
Praziquantel is an antiparasitic known for its efficacy against the tapeworm class of parasites. The drug damages the parasites skin leading to disintegration. Worms are not commonly seen in the feces in response to treatment.

How is praziquantel given and what if a dose is missed?
Praziquantel is typically prescribed as a single dose medication.

How should praziquantel be stored?
Store at room temperature and protected from light.

What side effects are associated with praziquantel?
Gastrointestinal signs including appetite loss, vomiting, and diarrhea occur in approximately 5% of patients taking praziquantel. The oral formulation may taste bitter to pets.

What drugs should not be given with praziquantel?
There are no specific drug interactions of major concern.

What follow up is necessary with praziquantel use?
Prevention of future re-exposure is recommended via flea and rodent control. Follow up fecal examination is recommended a week after treatment is completed.